New approaches in super-resolution imaging

Benedict Diederich und Alexander Jügler

"With the film project, I hope to encourage more people into the micro-world of cells and microscopic objects and to inspire them to get creative with the combination of different technologies which are widely spread already." (Benedict Diederich)

"I especially am motivated to apply physical methods to solve biological and medical problems." (Alexander Jügler)

The two research projects

With the help of neural networks and machine learning, Benedict Diederich attempts to reconstruct the variation of the refractive index of a cell in the three-dimensional volume. Multiple scatter effects within the sample are taken into account, which should lead to results that are more exact. The data should be recorded in the long term using a standard light microscope. Incidentally, the two scientists are trying to make this partially very cost-intensive technology available to the masses in the form of 3D printed microscopes.

Alexander Jügler develops new methods and devices for super-resolution imaging. He tries to improve further the noble price awarded localization microscopy with a holographic approach. Using this new imaging method, we want to characterize intracellular infections of fungi, which are often lethal for immunocompromised persons.

Vita Benedict Diederich

  • seit 2016: Promotion am IPHT Leibniz Insitut Jena
  • 2015 - 2016: Carl Zeiss Microscopy GmbH Göttingen
  • 2013 - 2015: IPT Fraunhofer Institut Aachen - Bachelorarbeit/HIWI
  • 2011 - 2016: Bachelor/Master Elektrotechik/Optische Technologien; TH Köln
  • 2010 - 2011: L'arche Hamilton, Living Assistant, Civilian Service/Zivildienst
  • 2006 - 2009: Miele & Cie Kg. technische Ausbildung als Elektroniker für Betriebstechnik

Vita Alexander Jügler

  • PhD Physics (Optics) - Leibniz Institute of Photonic Technology (Jena)
  • Research stations: Kirchhoff-Institute for Physics (Heidelberg), Institute of Molecular Biology (Mainz), Department of Biology (York, UK), Department of Biochemistry/Micron (Oxford), Max-Planck-Institute of Neurobiology (Martinsried)
  • Study abroad - University of York (UK), University of Oxford (UK)
  • Physics studies (BSc, MSc) - University of Heidelberg
  • Apprenticeship: Investment Fund Specialist (IHK), International Management Assistant (AHK)  - DWS Holding & Service
  • Interests: Biophysics, sports (skiing, scuba diving, martial arts, gliding), politics, volunteering (Round Table Jena)

Further information

Leibniz-Institut für Photonische Technologien